Laron syndrome is a genetic condition that affects how the body uses growth hormone, here's a breakdown in 7 points.
1
Individuals with untreated Laron syndrome reach a significantly shorter adult height compared to the average population.
2
The body produces growth hormone, but it cannot utilize it effectively due to a problem with growth hormone receptors.
3
Mutations in the GHR gene, responsible for growth hormone receptors, cause Laron syndrome.
4
Reduced muscle strength, low blood sugar in infancy, delayed puberty, and specific facial features are some additional symptoms.
5
A flattened nose bridge and a small jaw are some facial features often associated with Laron syndrome.
6
Treatment focuses on providing the body with what it lacks - injections of insulin-like growth factor 1 (IGF-1) can help improve growth.
7
Laron syndrome falls within a spectrum of conditions affecting the growth hormone pathway.